Certain genetic mutations can lead to increased muscle mass in humans.

Mutations in specific genes, such as the myostatin gene, can result in individuals having significantly more muscle mass than average. For example, individuals with a mutation in both copies of the myostatin gene tend to have increased muscle size and strength, a condition known as double-muscling. This genetic variation has been studied in various animal species as well, offering insights into muscle development and potential applications in agriculture and medicine for conditions related to muscle wasting. Understanding these genetic factors can also provide valuable information for athletes and trainers seeking to optimize performance.